| Titre : |
Préparation d'une nnoformulation à base de l'huile essentielle de cymbopogon winterianus et l'évaluation de ses activités biologiques |
| Type de document : |
texte imprimé |
| Auteurs : |
Radjia Djaalab, Auteur ; Imene Mellah, Auteur ; Cheimaa Bouchekouk, Auteur |
| Editeur : |
Tipaza [Algérie] : Centre universitaire Morsli Abdellah - Tipaza- |
| Année de publication : |
2023/2024 |
| Importance : |
p.61 |
| Présentation : |
couv. en coul., ill., fig. |
| Format : |
30 cm |
| Accompagnement : |
CD |
| Note générale : |
Bibliographie:p47-61. |
| Langues : |
Français (fre) Langues originales : Français (fre) |
| Catégories : |
Microbiologie
|
| Mots-clés : |
Cymbopogon winterianus EO GC-MS NE antibacterial activity anti-inflammatory. |
| Index. décimale : |
579.09/M |
| Résumé : |
The global search for natural alternatives to synthetic compounds is incteasing, with Algeria focusing on essential oils(HE). Volatil mixtures are considered delicate and unstable. To address this issue, HE-based nanoemulsions (NE) have been considered a novelty. This study aims to prepare a HE-based NE from java citronella and evaluate ist biological activitiies.
EO was extracted by vapo-hydrodistillation. Chemical characterization was carried out by gas chromatography/mass spectrometry (GC/MS) and physico-chemical index analysis. The extracted HE was subjected to spontaneous emulsification in the presence of Tween 80. Both the NE obtained and the lemongrass EO showed antibacterial activity against 3 ATCC strains (Escherichia coli, pseudomonas aeruginosa, staphylococcus aureus), as well as anti-inflammatory activity using the BSA protein denaturation test.
The GC-MS results for the EO studied showed the predominance of citronellal (18.10%), geraniol (16.23%) and citronello (10.91%). The physicochemical indices studied endorsed the good quality of C. winterianus EO. on the other hand, tween 80 successfully encapsulated the EO and produced a xhite-colored NE. In addition, nanoparticles loaded with lemongrass oil showed superior antibacterial activity to EO against E. coli and P. aeruginosa. On the other hand, S. aureus was more sensitive to EO than NE. The results of anti-inflammatory activity showed an absence of an anti-inflammatory effect at the concentrations tested. |
Préparation d'une nnoformulation à base de l'huile essentielle de cymbopogon winterianus et l'évaluation de ses activités biologiques [texte imprimé] / Radjia Djaalab, Auteur ; Imene Mellah, Auteur ; Cheimaa Bouchekouk, Auteur . - Tipaza [Algérie] : Centre universitaire Morsli Abdellah - Tipaza-, 2023/2024 . - p.61 : couv. en coul., ill., fig. ; 30 cm + CD. Bibliographie:p47-61. Langues : Français ( fre) Langues originales : Français ( fre)
| Catégories : |
Microbiologie
|
| Mots-clés : |
Cymbopogon winterianus EO GC-MS NE antibacterial activity anti-inflammatory. |
| Index. décimale : |
579.09/M |
| Résumé : |
The global search for natural alternatives to synthetic compounds is incteasing, with Algeria focusing on essential oils(HE). Volatil mixtures are considered delicate and unstable. To address this issue, HE-based nanoemulsions (NE) have been considered a novelty. This study aims to prepare a HE-based NE from java citronella and evaluate ist biological activitiies.
EO was extracted by vapo-hydrodistillation. Chemical characterization was carried out by gas chromatography/mass spectrometry (GC/MS) and physico-chemical index analysis. The extracted HE was subjected to spontaneous emulsification in the presence of Tween 80. Both the NE obtained and the lemongrass EO showed antibacterial activity against 3 ATCC strains (Escherichia coli, pseudomonas aeruginosa, staphylococcus aureus), as well as anti-inflammatory activity using the BSA protein denaturation test.
The GC-MS results for the EO studied showed the predominance of citronellal (18.10%), geraniol (16.23%) and citronello (10.91%). The physicochemical indices studied endorsed the good quality of C. winterianus EO. on the other hand, tween 80 successfully encapsulated the EO and produced a xhite-colored NE. In addition, nanoparticles loaded with lemongrass oil showed superior antibacterial activity to EO against E. coli and P. aeruginosa. On the other hand, S. aureus was more sensitive to EO than NE. The results of anti-inflammatory activity showed an absence of an anti-inflammatory effect at the concentrations tested. |
|  |