Titre :	Evaluation des activités biologiques des algues brunes issues de la côte de Tipaza
Type de document :	texte imprimé
Auteurs :	Amel Cheurfi, Auteur ; Sabah Gheddouchi, Auteur
Editeur :	Tipaza [Algérie] : Centre universitaire Morsli Abdellah - Tipaza-
Année de publication :	2024/2025
Importance :	p.74
Présentation :	couv. en noir et blanc ., ill., fig.
Format :	30 cm
Accompagnement :	CD
Note générale :	Bibliographie: p61-70. Annexes: p72-73.
Langues :	Français (fre)
Catégories :	Microbiologie
Mots-clés :	Fucus vesiculosus  sulfated polysaccharides  aqueous extraction  FTIR  NMR  antioxidant activity  antifungal activity  antibacterial activity  brown algae  marine resource valorization.
Index. décimale :	579.34
Résumé :	This work is part of a valorization approach of marine resources, specifically focusing on brown algae of the Fucus genus, known for their richness in bioactive polysaccharides. The main objective of this study was to extract, characterize, and evaluate the biological properties of a polysaccharide extract from Fucus vesiculosus. The extraction was performed using hot water, followed by lyophilization, resulting in a yield of 6.5%. Initial spectroscopic characterization (UV-Visible) was conducted to estimate extract purity, and complementary techniques (FTIR, NMR) were used to confirm the chemical nature of the isolated compounds. Biological evaluation revealed strong antioxidant activity, with a radical scavenging rate of 92.31%, confirming the antioxidant potential of sulfated polysaccharides in the algae. Antibacterial testing showed no inhibitory activity against tested strains (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, Salmonella spp.), likely due to structural limitations or low diffusion across bacterial membranes. However, a 6 mm inhibition zone was observed against Candida albicans, exceeding that of the reference antifungal, suggesting a moderate but notable fungistatic effect. These findings highlight the pharmacological and cosmetic potential of marine algal polysaccharide extracts, particularly in the development of natural antifungal or antioxidant agents. Further studies should explore extraction optimization, active fraction purification, and mechanisms of action.

Evaluation des activités biologiques des algues brunes issues de la côte de Tipaza [texte imprimé] / Amel Cheurfi, Auteur ; Sabah Gheddouchi, Auteur . - Tipaza [Algérie] : Centre universitaire Morsli Abdellah - Tipaza-, 2024/2025 . - p.74 : couv. en noir et blanc ., ill., fig. ; 30 cm + CD.
Bibliographie: p61-70.
Annexes: p72-73.
Langues : Français (fre)

Catégories :	Microbiologie
Mots-clés :	Fucus vesiculosus  sulfated polysaccharides  aqueous extraction  FTIR  NMR  antioxidant activity  antifungal activity  antibacterial activity  brown algae  marine resource valorization.
Index. décimale :	579.34
Résumé :	This work is part of a valorization approach of marine resources, specifically focusing on brown algae of the Fucus genus, known for their richness in bioactive polysaccharides. The main objective of this study was to extract, characterize, and evaluate the biological properties of a polysaccharide extract from Fucus vesiculosus. The extraction was performed using hot water, followed by lyophilization, resulting in a yield of 6.5%. Initial spectroscopic characterization (UV-Visible) was conducted to estimate extract purity, and complementary techniques (FTIR, NMR) were used to confirm the chemical nature of the isolated compounds. Biological evaluation revealed strong antioxidant activity, with a radical scavenging rate of 92.31%, confirming the antioxidant potential of sulfated polysaccharides in the algae. Antibacterial testing showed no inhibitory activity against tested strains (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, Salmonella spp.), likely due to structural limitations or low diffusion across bacterial membranes. However, a 6 mm inhibition zone was observed against Candida albicans, exceeding that of the reference antifungal, suggesting a moderate but notable fungistatic effect. These findings highlight the pharmacological and cosmetic potential of marine algal polysaccharide extracts, particularly in the development of natural antifungal or antioxidant agents. Further studies should explore extraction optimization, active fraction purification, and mechanisms of action.