| Titre : |
Évaluation des effets synergiques des huiles essentielles de syzygium aromaticum (L.) (clou de girofle) et origanum vulgare (L.) (origan): impact biologique et thérapeutique |
| Type de document : |
texte imprimé |
| Auteurs : |
Khaoula Ouadah, Auteur ; Mounira Kadous, Auteur ; Z Hadjou, Auteur |
| Editeur : |
Tipaza [Algérie] : Centre universitaire Morsli Abdellah - Tipaza- |
| Année de publication : |
2024/2025 |
| Importance : |
p.76 |
| Présentation : |
couv. en noir et blanc ., ill., fig.,tabl. |
| Format : |
30 cm |
| Accompagnement : |
CD |
| Note générale : |
Bibliographie: p57-76. |
| Langues : |
Français (fre) |
| Catégories : |
Microbiologie
|
| Mots-clés : |
Syzygium aromaticum (L.) Origanum vulgare (L.) essential oil antibacterial activity synergistic effect DPPH. |
| Index. décimale : |
579.48 |
| Résumé : |
In response to the alarming rise of antibiotic resistance, this study aims to evaluate the antibacterial and antioxidant efficacy of two essential oils (EOs) extracted from aromatic plants traditionally used in Algeria: Syzygium aromaticum (L.) (clove) and Origanum vulgare (L.) (oregano). The EO of O. vulgare was obtained by steam distillation, with a yield of 0.95%.
The antibacterial activity was assessed in vitro against eight pathogenic clinical bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Enterococcus faecalis, Shigella dysenteriae, Providencia rettgeri) using two complementary methods: the aromatogram and the micro-atmosphere technique. The results showed significant antibacterial activity for both EOs, with enhanced effectiveness when combined. The synergistic effect proved particularly effective against most tested strains, although some resistance was noted in P. aeruginosa. These findings highlight the therapeutic potential of this combination in combating multidrug-resistant bacteria.
Furthermore, antioxidant activity was evaluated using the DPPH free radical scavenging assay. The extracts exhibited notable antiradical potential, especially the EO of S. aromaticum, which showed an IC₅₀ of 74.90 ± 0.73 µg/mL, indicating strong antioxidant activity.
In conclusion, the synergy between S. aromaticum and O. vulgare essential oils offers a promising natural alternative to conventional antibiotics and antioxidants, with potential applications in medicine and pharmacy.
|
Évaluation des effets synergiques des huiles essentielles de syzygium aromaticum (L.) (clou de girofle) et origanum vulgare (L.) (origan): impact biologique et thérapeutique [texte imprimé] / Khaoula Ouadah, Auteur ; Mounira Kadous, Auteur ; Z Hadjou, Auteur . - Tipaza [Algérie] : Centre universitaire Morsli Abdellah - Tipaza-, 2024/2025 . - p.76 : couv. en noir et blanc ., ill., fig.,tabl. ; 30 cm + CD. Bibliographie: p57-76. Langues : Français ( fre)
| Catégories : |
Microbiologie
|
| Mots-clés : |
Syzygium aromaticum (L.) Origanum vulgare (L.) essential oil antibacterial activity synergistic effect DPPH. |
| Index. décimale : |
579.48 |
| Résumé : |
In response to the alarming rise of antibiotic resistance, this study aims to evaluate the antibacterial and antioxidant efficacy of two essential oils (EOs) extracted from aromatic plants traditionally used in Algeria: Syzygium aromaticum (L.) (clove) and Origanum vulgare (L.) (oregano). The EO of O. vulgare was obtained by steam distillation, with a yield of 0.95%.
The antibacterial activity was assessed in vitro against eight pathogenic clinical bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Enterococcus faecalis, Shigella dysenteriae, Providencia rettgeri) using two complementary methods: the aromatogram and the micro-atmosphere technique. The results showed significant antibacterial activity for both EOs, with enhanced effectiveness when combined. The synergistic effect proved particularly effective against most tested strains, although some resistance was noted in P. aeruginosa. These findings highlight the therapeutic potential of this combination in combating multidrug-resistant bacteria.
Furthermore, antioxidant activity was evaluated using the DPPH free radical scavenging assay. The extracts exhibited notable antiradical potential, especially the EO of S. aromaticum, which showed an IC₅₀ of 74.90 ± 0.73 µg/mL, indicating strong antioxidant activity.
In conclusion, the synergy between S. aromaticum and O. vulgare essential oils offers a promising natural alternative to conventional antibiotics and antioxidants, with potential applications in medicine and pharmacy.
|
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579.01 
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